Public Health Software
My research at UT Dallas and UT Southwestern Medical Center has been focused on spatial statistics, Bayesian modeling, and public health. This page describes the main products of this work, which include papers on quantitative methodology and a pair of software programs that implement the methods. The software and code uses the R language for statistical computing and the Stan modeling language for Markov chain Monte Carlo sampling.
The geostan R package
Donegan, Connor (2022). geostan: An R package for Bayesian spatial analysis. The Journal of Open Source Software 7, no. 79: 4716 DOI:10.21105/joss.04716
The geostan R package supports a complete spatial analysis workflow with Bayesian models for areal data, including a suite of functions for visualizing spatial data and model results. Users can model censored outcomes—a common feature of vital statistics and disease registry data—and access spatial measurement error models, designed for working with American Community Survey (ACS) estimates.The package offers spatial methods suitable for modeling both count and continuous outcome data types.
Online documentation: connordonegan.github.io/geostan
Donegan, Connor (2021). Building spatial conditional autoregressive (CAR) models in the Stan programming language. OSF Preprints. DOI:10.31219/osf.io/3ey65
Donegan, Connor, Yongwan Chun and Daniel A. Griffith (2021). Modeling community health with areal data: Bayesian inference with survey standard errors and spatial structure International Journal of Environmental Research and Public Health 18, no. 13: 6856. DOI:10.3390/ijerph18136856 Supplementary material: https://github.com/ConnorDonegan/survey-HBM.
Donegan, Connor, Yongwan Chun and Amy E. Hughes (2020). Bayesian estimation of spatial filters with Moran's eigenvectors and hierarchical shrinkage priors. Spatial Statistics 38: 100450. DOI:10.1016/j.spasta.2020.100450 Pre-print URL: https://osf.io/fah3z/
The surveil R package
Donegan, Connor, Amy E Hughes and Simon J Craddock Lee (2022). Colorectal Cancer Incidence, Inequalities, and Prevention Priorities in Urban Texas: Surveillance Study with the "surveil" software package. JMIR Public Health & Surveillance 8, no. 8: e34589 DOI:10.2196/34589 PMID:35972778
The surveil R package provides time series models for routine public health surveillance tasks: model time trends in mortality or disease incidence rates to make inferences about levels of risk, cumulative and period percent change, age-standardized rates, and health inequalities. This software provides an accessible alternative to joinpoint regression. Basic usage requires introductory-level R programming skills.
Online documentation: connordonegan.github.io/surveil
Donegan, Connor, Amy E Hughes and Simon J Craddock Lee (2022). Time Series Models for Public Health Surveillance: Colorectal Cancer Incidence, Inequalities, and Prevention Priorities in Urban Texas. Poster presentation to the Interdisciplinary Association of Population Health Science (IAPHS), Minneapolis, MN. Poster PDF.
Donegan, Connor (2021). "Building spatial conditional autoregressive (CAR) models in the Stan programming language." OSF Preprints. DOI: 10.31219/osf.io/3ey65 Supplementary material: https://osf.io/ewxut/.
This paper provides computationally efficient R and Stan code for building spatial conditional autoregressive (CAR) models in Stan. The paper details various CAR model specifications and demonstrates how users can use the geostan R package to facilitate the process of building custom spatial models in Stan. A demonstration analysis of county mortality rates also shows how to adjust for censored count data.
Donegan, Connor and Mitzi Morris (2021). "Flexible functions for ICAR, BYM, and BYM2 models in Stan.” Code repository. https://github.com/ConnorDonegan/Stan-IAR
This code repository contains a set of functions in the R and Stan programming languages that make it easier to implement the BYM and BYM2 spatial models in RStan. The code addresses multiple challenges that arise when using a disconnected graph structure with the intrinsic conditional autoregressive model. The functions support the construction of custom spatial models in Stan, and are also used by the geostan R package.